Ellasaurus Product Essay Example for Free

Ellasaurus Product Essay Ellen will use some copyrighted illustrations from her books on the Website. She will also include themes from the story lines of her books in some of the games that will be available (free) on the site to registered visitors. What are at least two intellectual property issues that might arise in the operation of the website? The first intellectual issue in the operation of the website will be in relation to the copyrighted illustration and contents which will be used on the website. Ellen will need to ensure that such use of copyrighted content does not violate intellectual property laws and due permission and authorization is taken from the owners of such copyrighted content, ie, the publisher of the books. Secondly, the games used on the website should be proprietary and if such games are taken from another website, permission from the owner of such content should be taken in advance. Ellen cannot display any proprietary or copyrighted content from another website or from any other source. Permission should be taken in advance and legal formalities should be completed before using any such material. What are some of the potential ethical issues that Ellen faces because of the ages of her intended audience? The primary ethical issue, due to the age of the target audience, is that the content of the website should be carefully developed so as to ensure that it is fully appropriate for the children and kids visiting the website. The owner of the websites should be ethically conscious in creating content that does not impart any wrong message to small kids and should enhance their knowledge and does not result in any harm. For example, the site should not display pornographic content. What are some of the laws with which the site must comply with when it registers site visitors under the age of 13? What are some recommendations regarding how Ellen can best comply with those laws? One of the laws is that the site does not knowingly collect or solicit Personally Identifiable Information from or about children under 13 except as permitted by law. Another one is that Company will not disclose information collected from children under the age of thirteen (13) (or from adults for that matter) to third parties unless indicated otherwise or in special cases where Company has reason to believe that disclosure is necessary to identify, contact or bring legal action against someone who may be causing injury to or interference (whether intentionally or unintentionally) with Companys rights or property or anyone else who may be harmed by such actions or if required by law Ellen can best comply with such laws by hiring the services of a lawyer or legal professional who has significant expertise with cyber laws.

Aldo Leopolds A Sand County Almanac Essay -- Aldo Leopold Sand County

Aldo Leopold's A Sand County Almanac Although Leopold’s love of great expanses of wilderness is readily apparent, his book does not cry out in defense of particular tracts of land about to go under the axe or plow, but rather deals with the minutiae, the details, of often unnoticed plants and animals, all the little things that, in our ignorance, we have left out of our managed acreages but which must be present to add up to balanced ecosystems and a sense of quality and wholeness in the landscape. Part I of A Sand County Almanac is devoted to the details of a single piece of land: Leopold’s 120-acre farmed-out farmstead in central Wisconsin, abandoned as a farm years before because of the poor soil from which the "sand counties" took their nickname. It was at this weekend retreat, Leopold says, "that we try to rebuild, with shovel and axe, what we are losing elsewhere". Month by month, Leopold leads the reader through the progression of the seasons with descriptions of such things as skunk tracks, mouse economics, the songs, habits, and attitudes of dozens of bird species, cycles of high water in the river, the timely appearance and blooming of several plants, and the joys of cutting one’s own firewood. In Part II of A Sand County Almanac, titled "The Quality of Landscape," Leopold takes his reader away from the farm; first into the surrounding Wisconsin countryside and then even farther, on an Illinois bus ride, a visit to the Iowa of his boyhood...

The Testosterone And Suicide Health And Social Care Essay

Testosterone is produced from cholesterin in the Leydig cells in the testicle. Testosterone synthesis in the foetal human testicle begins during the 6th hebdomad of gestation. Leydig cell distinction and the initial early testosterone production in the foetal testicle are independent of luteinizing endocrine ( LH ) ( 5, 6, 7 ) . During testicle development production of testosterone occurs under the influence of LH which is produced by the pituitary secretory organ. Synthesis and release of LH is regulated by the hypothalamus through gonadotropin-releasing endocrine ( GnRH ) and inhibited by testosterone via a negative feedback cringle ( 8 ) . Testosterone is metabolized in some tissues to a more active metabolite, 5I ±-dihydrotestosterone. Testosterone is present in the blood as free ( unbound ) testosterone, albumin edge and sex hormone-binding globulin ( SHGB ) -bound testosterone ( 5-8 ) . Testosterone is a C19 steA ¬roid with an unsaturated bond between C-4 and C-5, a ketone group in C-3 and a hydroxyl group in the B place at C-17. It is largely produced in the tesA ¬tes of males and the ovaries of females, although little sums of testosterone are produced by the adrenal secretory organs. Testosterone is found in mammals and other craniates. Blood testosterone degrees are much greater in males than in females: an grownup male organic structure produces about ten-times more testosterone than an big female organic structure. Females are more sensitive to testosterone than males. Testosterone regulates male sexual development and affects musculus strength, degrees of red blood cells, bone denseness, sense of wellbeing and sexual and generative map in both males and females. SHBG concentrations may be decreased or increased in many often observed medical conditions. In clinical pattern, alterations in SBHG are critically of import to see in the diagnosing of male hypogonadism. Because plasma entire testosterone concentrations are affected by changes in SHBG degrees, precise measurings of free or bioavailable testosterone are necessary to measure the sufficiency of Leydig cell map, to clear up whether a patient is hypogonadal, and to supervise the testosterone replacing intervention in patients with alterations in go arounding SHBG concentrations. Testosterone and self-destruction Multiple surveies suggest that testosterone plays a function in the ordinance of temper and behaviour. The research surveies of the relationship between testosterone and self-destructive behaviour produced variable consequences ( 9-14 ) . Some ( 10-13 ) but non all ( 14,15 ) probes of the relationship between testosterone and suicidality found assoA ¬ciations between testosterone and self-destructive behaviour. Tripodianakis et Al. compared plasma testosterone concentrations in work forces after a suicide effort with testosterone degrees in healthy work forces of the same age ( 10 ) . The writers found that the self-destruction triers had lower testosterone degrees compared with controls, and that the triers who used violent methods had lower plasma testosterone concentrations compared with the nonviolent triers. Markianos et Al. examined plasma testosterone degrees in a group of male psychiatric patients who had attempted to perpetrate self-destruction by leaping, in a group of male topics who were hospitalized after accidentally falling from a high tallness and in healthy controls ( 11 ) . Both accident and suicide effort patients had lower testosterone degrees compared with the control group, and at that place was a tendency towards lower testosterone degrees in self-destruction triers compared with the accident group. We have late examined whether there is a relation between plasma test osterone degrees and clinical parametric quantities in bipolar self-destruction triers and found that testosterone degrees positively correlated with the figure of frenzied episodes and the figure of suicide efforts ( 12 ) . Some other observations have shown that testosterone/anabolic androgenic steroids may play a function in the pathophysiology of suicidality ( 13 ) . A recent survey found no difference between male self-destruction triers and male controls with respect to plasma testosterone degrees ( 14 ) . A survey of associations between neuroactive steroids and suicidality in military veterans with posttraumatic emphasis upset besides found no association between serum testosterone degrees and a history of a suicide effort ( 15 ) . Disappointment over rejections at efforts for sexual interactions has been cited several decennaries ago as an of import trigger for self-destruction ( 16 ) . Impending divorce, matrimonial troubles, menace of losing a love spouse and rejection by a loved one were besides regarded as motivations for self-destruction for many old ages ( 17 ) . It has been observed that rejection of sexual intercourse was frequently associated with male self-destructions and self-destructive ideation ( 18 ) . A nexus between testosterone and the neurobiology of self-destructive behaviour may be related to ( 9 ) : a ) A direct consequence of testosterone on suicidality via certain encephalon mechanisms ; and/or B ) A testosterone consequence on aggression and, accordingly, suicidality ; and/or degree Celsius ) A testosterone consequence on temper and, accordingly, suicidality ; and/or vitamin D ) A testosterone consequence on knowledge and, accordingly, suicidality. Testosterone and self-destructive behaviour in striplings and immature grownups Suicide and testosterone/anabolic androgenic steroids At least one survey has demonstrated a relation between high degrees of testosterone and self-destruction in immature people ( 19 ) . Twenty-nine topics ( 17 self-destructions, 12 sudden deceases ) in the ages 23 to 45 old ages were included in the survey. Analysis indicated no important difference in ages between the two groups of topics ( suicide M = 33.35 yr. , sudden decease M = 35.67 yr. ) . There was a important difference in the average testosterone degree ( P & lt ; 0.007 ) between victims of self-destruction ( M = 376.41?183.64 ng/ml ) and victims of sudden decease ( M= 241.83?117.3 ng/ml ) . Eight instances of self-destruction, in 21- to 33-year-old males, with a history of current or recent usage of anabolic androgenic steroids ( AAS ) have been described in a instance series study ( 20 ) . Five self-destructions were committed during current usage of AAS, and two following 2 and 6 months after AAS backdown. The writers suggested that long-run usage of AAS may lend to completed self-destruction in predisposed individuals. A possible function of aggression A important figure of surveies suggest that high testosterone degrees are associated with aggression ( 9 ) . It has been shown that violent individuals have higher plasma, spit and CSF testosterone degrees compared to non-violent controls ( 21-23 ) . For illustration, in a survey of unprompted wrongdoers with alcohol addiction and antisocial personality upset, higher CSF testosterone degrees were observed compared to healthy controls ( 24 ) . The writers proposed that high CSF testosterone degrees may be associated with aggressiveness or interpersonal force. In the same paper, the writers reviewed the scientific literature on the nexus of testosterone to aggression in worlds, and proposed that both a insistent form of aggressive behaviour get downing early in life, and a insistent form of aggressive behaviour under the consequence of intoxicant are associated with increased degrees of testosterone. Research workers have observed that persons having testosterone are more likely to hol d an aggressive reaction to comprehend menaces than topics having placebo ( 25-27 ) . Fluctuations of testosterone concentration may be associated with aggression and temper alterations in striplings ( 28-30 ) . Salivary testosterone concentrations were evaluated in 40 kids, aged 7-14 old ages ( 37 male childs and three misss ) , with a history of aggressive behaviours and an association between higher testosterone degrees and aggressive behaviours was observed ( 29 ) . In another survey of stripling males, higher testosterone degrees were associated with aggravated verbal and physical aggression, a determination proposing that reactive unprompted aggression is correlated with higher testosterone degrees ( 30 ) . Fifty-eight healthy 15-17 twelvemonth old male childs, public school pupils participated in this survey. A high degree of testosterone led to an amplified preparedness to react energetically and forcefully to aggravations and menaces. Testosterone besides had an indirect and less strong consequence on another aggression dimension: high plasma concentrations o f testosterone made the male childs less patient and more cranky, which in bend intensified their sensitivity to prosecute in aggressive-destructive behaviour. The fact that higher testosterone degrees were associated with aggravated verbal and physical aggression suggests that reactive unprompted aggression correlatives with higher testosterone degrees. Therefore, aggression may medicate the consequence of high testosterone degrees on self-destructive behaviour in striplings and immature grownups. Not all surveies have observed differences in testosterone degrees between aggressive and unaggressive male childs ( 31 ) . A survey of 4-10 twelvemonth olds found no grounds of a relationship between testosterone degrees and aggressive behaviours. This indicated that such a relationship may be nonexistent in prepubescent kids. Animal theoretical accounts have contributed of import informations sing the effects of anabolic androgenic steroid ( AAS ) usage on aggression ( 32,33 ) . For illustration, surveies in gnawers confirmed that exposure to the AASs testosterone and Durabolin additions aggression. A side consequence of AAS usage reported in worlds is â€Å" roid fury, † a province of unselective and motiveless aggression. It has besides been observed that pubertal rats having AASs respond suitably to societal cues and they are more aggressive toward integral males than are eunuchs. Testosterone-treated male rats are most aggressive in their place coop. Probably, adolescent AAS exposure may increase aggressive behaviours. Some writers have postulated that there are significant similarities between aggression against the ego and aggression against others, based on the clinical and epidemiological observations that some suicide triers may portion personality traits with violent felons ( 34 ) . We have besides observed an association between aggression and self-destructive behaviour in our surveies ( 35,36 ) . For illustration, we have observed that a history of suicide effort in bipolar upset is associated with lifetime aggressive traits ( 35 ) . We have besides shown that the higher prevalence of suicide triers among down patients with a history of alcohol addiction compared to down patients without a history of alcohol addiction was related to higher aggression tonss in the group with alcohol addiction ( 36 ) . In drumhead, high testosterone degrees may be associated with self-destructive behaviour in striplings and immature grownups. This consequence of testosterone on suicidality in striplings and immature grownups may be mediated by testosterone-related elevated aggression. It is besides possible that in immature people, high testosterone degrees are straight linked to suicidality via certain encephalon mechanisms. Testosterone and self-destructive behaviour in older work forces Testosterone lack or hypotestosteronemia is a normally known hormonal alteration associated with male aging ( 37-39 ) . The prevalence of testosterone lack may be every bit high as 30 % in work forces aged 40-79 old ages ( 40,41 ) . In up to 12 % of affected work forces, hypotestosteronemia can be associated with clinical symptoms ( 40,41 ) . Age-related plasma testosterone lessening is a consequence of different biological changes such as primary structural gonadal harm, age-related degenerative alterations of the pituitary secretory organ, inadequacies of the neurohypothalamic system, and primary peripheral metabolic abnormalcies such as the age-associated addition in the concentration of serum sex endocrine adhering globulin ( SHBG ) , with a attendant lessening in free testosterone ( 39 ) . In the aging adult male, there is about a 1-2 % lessening of entire testosterone degrees per twelvemonth with a more rapid bead in free testosterone degrees because of a attendant addition in SHBG with aging. Because of this gradual lessening in testosterone degrees the androgen lack of the aged adult male is defined as partial androgen lack of the aging male ( PADAM ) or late oncoming hypogonadism ( LOH ) . Symptoms of testosterone lack in work forces include sexual symptoms ( such as reduced erectile map and lessened libido ) , reduced musculus and increased fat mass, and reduced bone denseness among others. It is ill-defined whether aging is to be considered as the lone variable linked to age-related testosterone lessening. Assorted facets such as familial factors, chronic diseases, medicines, fleshiness, and the life style may impact the testosterone metamorphosis ( 37,42-44 ) . Decreased testosterone degrees are associated with depressive symptoms, hapless cognitive map and Alzheimer ‘s disease ( 9,45-48 ) . In fact, increased incidence of hypogonadism is observed in work forces with major depression ( 9,47 ) . Depressed work forces often have low plasma or serum testosterone ( 9,48 ) . Testosterone has mood-enhancing belongingss and antidepressant effects in work forces ( 9,49-51 ) . Testosterone replacing efficaciously improves temper. Testosterone users sometimes develop frenzied or hypomanic symptoms during testosterone usage and depressive symptoms during testosterone backdown ( 52-55 ) . In gnawers, testosterone has antidepressant effects in elderly male mice and protective effects against the development of depression-like behaviours in rats ( 56,57 ) . A recent survey found a testosterone-dependent ordinance of hippocampal ERK2 look which suggests that ERK2 signaling within the dentate gyrus country of the hippocampus is a critical go-between of the antidepressant belongingss of testosterone ( 58 ) . Experimental surveies suggest that testosterone has neuroprotective effects ( 59 ) . However, in intercession clinical research on aged work forces, testosterone replacing had a good influence on temper merely if work forces had clearly subnormal testosterone degrees ( 60 ) . It is of import note that sexual disfunction can hold a major consequence on the quality of life and emotional wellbeing ( 61,62 ) . The consequences of placebo-controlled randomised surveies of the effects of testosterone on the quality of life and down temper have been inconsistent and frequently the quality of life as assessed by different questionnaires did non better significantly ( 63 ) . Higher blood degrees of testosterone are associated with better cognitive operation, particularly in older work forces ( 45,46 ) . For illustration, greater serum degrees of testosterone late in life predict a lower hazard of future Alzheimer ‘s disease development in older work forces ( 45 ) . Higher blood testosterone degrees are associated with better visuospatial abilities, semantic memory and episodic memory in work forces, with larger positive consequence with increasing age ( 46 ) . Both depression and cognitive damage are associated with self-destructive behaviour ( 64-67 ) . At least 60 % of persons who commit suicide suffer from depression. Hence, depression and cognitive damage may medicate the consequence of testosterone lack on suicidality in older work forces. This suggests that the intervention of hypogonadism in older work forces may better temper and knowledge, and accordingly, cut down self-destructive behaviour. Decision In drumhead, it is sensible to suggest that self-destructive behaviour in immature work forces is associated with high testosterone degrees while suicidality in older work forces is associated with reduced testosterone secernment. This indicates that the effects of testosterone on suicidality in work forces should be studied individually in immature and old persons. It is likely that plasma and salivary testosterone checks can assist in placing paediatric and grownup patients that would react best to certain interventions. Further surveies of the function of testosterone in the pathophysiology of psychiatric upsets and self-destructive behaviour are merited.

Should Children Develop Chronic Diseases From Vicious...

â€Å"My new born child was born. He was completely healthy and he was happy. He was on track; he was walking, learning to talk and interactive with the people around him. He was at his one-year check up and it was time for his next round of shots. Without question, his shots were given, weeks later he was diagnosed with autism.† There are endless stories of this exact circumstance. Vaccines have transformed into a part of american culture and new born children are rapidly being brought to these practices without their parents even questioning what is being injected into their newborns wholesome bodies. This affair must be addressed for the sake of poor innocent children developing chronic diseases from vicious vaccines. Deciding not to vaccinate a child can save potential that may be lost every time a child is vaccinated, instead parents should trust in their own child s immune system to fulfill the duties it was made to do without the need of vaccines. Several kids in america today have developed chronic disorders from vaccines, some do not even realize it! There are 3 million children in public schools under the classification of learning disabled today. In 1976 there were only 796,000 children (source 29). Children with these learning disabilities cannot thrive to their full potentials. Numerous parents reason that the benefits of vaccines outweigh the risks. But the risks are increasing, children are getting asthma, autism, ADHD, diabetes, and rheumatoidShow MoreRelatedNo Needles: Why Vaccination Proponents Persuasive Methods are Counterintuitive1575 Words   |  7 PagesIt’s hard to imagine a world without vaccines—a world where â€Å"getting sick† had the potential to be fatal (or at least cause irreparable damage to one’s body). In this world, diseases robbed millions of bright-eyed children of their lives. Thankfully, though, with the development of vaccines, populations have grown larger and healthier over the past century. Sadly, despite the improved longevity of our species, many people are still undecided about—or vehemently against—childhood vaccination. TheyRead MoreCystic Fibrosis : An Autosomal Recessive Disease1757 Words   |  8 Pagesan autosomal recessive disease affecting nearly 1 in 2,500 of people of W estern European descent. The lifespan for anyone afflicted with cystic fibrosis ages from 30 to 40 years old with many complications presented throughout their life. These complications can include lung diseases that result in many different respiratory infections. Although cystic fibrosis is not a preventative nor curable disease, there are many different ways to help patients suffering from the disease by alleviating many ofRead MoreSubstance Abuse15082 Words   |  61 Pagesescape from reality. LIST FIVE WAYS IN WHICH EXCESSIVE ALCOHOL DRINKING MAY DAMAGE HEALTH Heavy drinking may enlarge the liver and passage of blood through it is slowed down. This increases the blood pressure putting extra stress on the heart muscle, which may also be damaged directly by the alcohol. * Cirrhosis of the liver The liver swells with fatty tissue, cells are destroyed and connective tissue is deposited. * Vitamin B1 is frequently deficient in alcoholics. * Bleeding from the stomachRead More‚Äà ºa Contemporary View on Health Care System in Bangladesh.‚Äà ¹14806 Words   |  60 Pagesreport. The second stage is the data collection stage. I have planned to collect data in three main phases. * Collect data from internet, different books and medical journals. * Conduct interviews with selected representatives from different level of health professionals. This phase actually concentrates on clarification and elaboration of data collected from the first phase. * Conduct interviews and communicate with health providers who are in the front line. This phase actually concentratesRead MoreDeveloping Management Skills404131 Words   |  1617 PagesWeidemann-Book Credits and acknowledgments borrowed from other sources and reproduced, with permission, in this textbook appear on appropriate page within text. Copyright  © 2011, 2007, 2005, 2002, 1998 Pearson Education, Inc., publishing as Prentice Hall, One Lake Street, Upper Saddle River, New Jersey 07458. All rights reserved. Manufactured in the United States of America. This publication is protected by Copyright, and permission should be obtained from the publisher prior to any prohibited reproduction